dPC™ Fractionator
The dPC™ Fractionator has the capacity to run up to 6 separate samples under controlled temperature, voltage, and mixing. The instrument is programmed to run samples from start to finish unattended.
The dPC™ Fractionator Workflow
The dPC™ technology easily integrates into existing mass spectroscopy workflows. Simply reduce, alkylate and desalt your sample before adding to the dPC™ running buffer. Separate for 30 minutes and your protein samples are ready for in-gel tryptic digestion then mass spec identification or your peptide samples are ready for mass spec identification.
The dPC™ technology is compatible with a wide variety of mass spectroscopy instrumentation. Alternatively, proteins can be identified by immunoblotting. The combination of the simple workflow and precise dPC™ manufacturing insures reproducibility from chip to chip and experiment to experiment.
Consommables pour Fractionator
Vidéo:
Brochure:
 The Power of Proteomics Unleashed
Notes d'applications:
LC/MS Workflow for Complex Cell Lysates
Reproducibility of the dPC™ for Complex Cell Lysates
Comparative Proteomics of Lipid Raft Proteins using the dPC™ or SDS-PAGE
Introduction to MSRAT-Key Features
Reproducibility of the dPC™ Manufacturing Process
Publications:
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biocompare.pdf (776kb)
Biocompare, Technology Spotlight, May 18, 2009
PROTEIN FOREST INC, Biocompare reviews popular technologies to include Protein Forest dPC® isoelectric fractionator. Protein Forest Inc. is top rated for improving reproducibility, offering reliable and sensitive sample prep. |
MicroScale Bioseparations 2009 Poster.pdf (367kb)
Poster presented at the MicroScale Bioseparations (MSB) Meeting, Boston, MA 2009 by the Barnett Institute of Chemical and Biological Analysis on the impact of the dPC on their study of the changes in the glycoproteome associated with breast cancer. |
HUPO_2009_New Workflow Poster.pdf (181kb)
Poster presented at the US HUPO 5th Annual Conference, San Diego, CA 2009 by the Thermo Fisher Scientific BRIMS Center and Protein Forest on a new workflow using the dPC that could be used clinically. |
ASMS 2009 TMT - dPC Poster.pdf (1.2mb)
Poster presented at 57th ASMS Conference on Mass Spectrometry and Allied Topics, Philadelphia, PA 2009 on a high-throughput quantitative workflow using both isobaric labels (Tandem Mass Tag, TMT, Thermo Scientific) and pI based fractionation (digital ProteomeChip®, dPC® to identify stroke biomarkers from patient plasma samples. |
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genomenews.pdf (164kb)
Genetic Engineering & Biotechnology News, Standardization in Biomarker Discovery "New Technology Designed to Provide Improved Coverage, Reproducibility, and Fast Separation", May 1, 2009 (Vol.29, No.9)
PROTEIN FOREST INC, Dr. James Dasch (director of scientific applications) highlighting key features of the dPC® fractionator system. This article reviews Protein Forest technology as the "go to" technology for improving biomarker discovery to include full coverage, high reproducibility and fast separation. |
HUPO_2008_iWB_Poster.pdf (224kb)
Poster presented at HUPO 7th World Congress, Amsterdam 2008 on a new technology, isoelectric Western Blotting (iWB), that eliminates protein "blow-through." |
HUPO_2008_MSRAT_Poster.pdf (356kb)
Poster presented at HUPO 7th World Congress, Amsterdam 2008 on use of the Mass Spec Results Analysis Tool® (MSRAT®) bioinformatics software to rapidly discover biologically significant results from MS database searches. |
UCSF Conference 2009 Peptide Poster.pdf (1.6 mb)
Poster presented at the 9th International Symposium on Mass Spectrometry in the Health and Life Sciences: Molecular and Cellular Proteomics, San Francisco, CA 2009 on a new technology that separates and concentrates peptide samples by isoelectric point using fully mass spec compatible buffers and conditions. |
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