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Anticorps >

Transduction du Signal

 

Anticorps anti Phosphatases Alcalines

Pour plus de renseignement, cliquez sur les descriptions:

 

Référence
Anticorps
Clone
Qté
Prix Unitaire
Euros HT
3523-01 Alkaline Phosphatase 
(Human Intestinal) Catalog #: 3523-01

Alkaline Phosphatase (Human Intestinal) Monoclonal Antibody

Alkaline phosphatase removes phosphate groups from the 5' end of DNA and RNA, and from proteins, at high pH. AAP.1 can be used in the diagnosis of tumors as some tumors produce intestinal ALP ectopically.

Antigen: Alkaline Phosphatase (Human Intestinal)

Clone number: AAP.1

Immunogen: D98/AH-2(HeLa) cells, which produce alkaline phosphatase ectopically.

Species Reactivity: ---

Host Species: Mouse: Balb/c

Applications: ELISA

Isotype: IgG2a

References: Arklie J et al. 1981. Tissue-Antigens. 17(3):303-12.

Brock DJ et al. 1985. Lancet. 1(8439):1175-8.

Notes: ---

Quantity: 100µg
AAP.1 
100 µg
266.00 EUR
3523-02 Placental Alkaline Phosphatase 
(PLAP)Catalog #: 3523-02

Placental Alkaline Phosphatase (PLAP) Monoclonal Antibody

Alkaline phosphatases are phosphodiesterases. The placental-specific isozyme of Alkaline Phosphatase (PLAP) is found in trophoblast cells of normal human mature placenta, seminomas of testis and ovarian carcinomas. Detection of alkaline phosphatase in serum is a marker for ovarian and testicular cancer. HD 8B6 has potential uses in the diagnosis of ovarian and testicular tumors. The antibody detects both Regan and Nagao isoenzymes.

Antigen: Placental alkaline phosphatase (PLAP)

Clone number: HD 8B6

Immunogen: Fresh Hep-2 cells followed by booster injections of fresh Hep-2 cells that had had their surface expression of PLAP boosted in culture.

Species Reactivity: Human

Host Species: Mouse: Balb/c

Applications: ELISA, IHC (P &F), RIA

Isotype: IgG2a

References: Durbin H et al. 1988. Int. J. Cancer Supplement. 2:50-58.
Durbin H et al. 1988. Int. J. Cancer Supplement. 2:59-66.

Notes: ---

Quantity: 100µg
HD 8B6
100 µg
266.00 EUR
3523-03 BCR-ABLCatalog #: 3523-03

BCR-ABL Monoclonal Antibody

The BCR gene is involved in the 9:22 translocation that generates the Philadelphia chromosome both in chronic myeloid leukemia (CML) and in a proportion of cases of acute lymphocytic leukemia (ALL). A 5' bcr sequence becomes fused to an abl sequence (including tyrosine kinase domain sequences) from chromosome 9 and results in the production of a chimaeric BCR-ABL protein with enhanced kinase activity. These antibodies may be useful for studies of the oncogene and have potential diagnostic and prognostic applications.

Antigen: BCR-ABL

Clone number: 7C6

Immunogen: Bcr686 thyroglobulin conjugate (Sequence: SSINEEITPRRQS)

Species Reactivity: Human

Host Species: Mouse: Balb/c

Applications: WB, IP, IF

Isotype: IgG2a

References: Dhut S et al. 1988. Oncogene 3:561-566.
Walker LC et al. 1987. Nature 329:851-853.

Notes: ---

Quantity: 100µg
7C6 
100 µg
266.00 EUR

 

Nous pouvons également vous proposer des services d'anticorps monoclonaux et polyclonaux.

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