Spécifique de tissus
Mucin 1 (Muc1) Antibody
MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoitic cell lineages. In the vast majority of human carcinomas, this protein is upregulated, poorly glycosylated and appears on the cell surface in a non-polarized fashion. SM3 antibody recognizes this under-glycosylated form of MUC1 and is therefore tumor specific.
Antigen: Mucin 1 (Muc1)
Clone number: 3M3
Immunogen: Hydrogen fluoride deglycosylated milk mucin
Species reactivity: Human
Host species: Mouse: Balb/c
Applications: IHC (P&F)
Isotype: IgG1
Reference: Burchell et al. 1987. Cancer Research. 47: 5476-82.
Burchell et al. 1989. Int J Cancer. 44: 691-6.
Notes: Reacts very little with normal tissue. Found to react with breast, colon and ovarian carcinomas and adinocarcinoma. Positive control: Ovarian, breast or colon carcinoma, normal intestine or colon.
Quantity: 100 μg
Référence |
Anticorps |
Clone |
Qté |
Prix
Unitaire
Euros HT |
| 3517-01 |
Mucin1 (Muc1) |
3M3 |
100 µg |
266.00 EUR |
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