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Anticorps
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Anticorps >

Régulation transcriptionnelle

Pour plus de renseignement, cliquez sur les descriptions:

Référence	Anticorps	Clone	Qté	Prix Unitaire Euros HT
3518-01	c-Jun (phosphorylated)Catalog #: 3518-01 c-Jun (phosphorylated) Monoclonal Antibody The product of the c-Jun oncogene plays an important role in the regulation of gene expression and signal transduction processes. Antigen: c-Jun (phosphorylated) Clone number: C-J 4C4/1 Immunogen: c-Jun of Jun oncogene phosphorylated at T91 and T93 Species reactivity: Human Host species: Mouse: Balb/c Applications: ELISA, WB Isotype: IgG1 References: Nateri AS et al. Science 2004, 303:1374-8 Notes: C-J 4C4 is known to recognize human and rat jun but the gene is highly conserved and so it may recognize other species. Quantity: 100 µg	C-J 4C4/1	100 µg	266.00 EUR
3518-02	c-MycCatalog #: 3518-02 c-Myc Monoclonal Antibody The c-Myc oncogene is a member of the Myc family of transcription factors that regulate cell proliferation and apoptosis. c-Myc is expressed in proliferating tissues and increased c-Myc expression is found in many cancers. Antigen: c-Myc Clone number: 9E10 Immunogen: AA 408-420 AEEQKLISEEDL Species reactivity: Human Host species: Mouse: Balb/c Applications: IP, IHC(F) Isotype: IgG1 References: Halme A et al. 2004. Cell. 116(3):405-15. Kari B et al. 1986. J. Virol. 60:345-352. Notes: --- Quantity: 100 µg	9E10	100 µg	266.00 EUR
3518-03	N-MycCatalog #: 3518-03 N-Myc Monoclonal Antibody The N-Myc oncogene is a member of the Myc family of transcription factors that regulate cell proliferation and apoptosis. N-Myc is amplified in a proportion of neuroblastoma patients. Antigen: N-Myc Clone number: NMYC-1 Immunogen: Human N-Myc peptide, sequence SPYVESEDAPPQKC conjugated to KLH. Species reactivity: Human, Mouse Host species: Mouse: Balb/c Applications: WB, IF Isotype: IgG2a kappa References: Kolodziej PA & Young RA. 1991. Methods Enzym. 194:508-519. Notes:--- Quantity: 100 µg	NMYC-1	100 µg	266.00 EUR
3518-04	PARNCatalog #: 3518-04 PARN Polyclonal Antibody PARN is a poly(A) specific 3'-5' exoribonuclease that has been implicated in the first step of eukaryotic messenger RNA decay; deadenylation. It is a member of the RNase D family of 3' exoribonucleases. The protein is found in both the nuclear and cytoplasmic fractions. Two isoforms have been observed - the full length 73kDa protein and a proteolytic product of ~53kDa. PARN is unique among deadenylases in that it interacts specifically with the 5' 7meGpppG cap structure of mRNAs and this interaction enhances its activity. PARN function is consequently inhibited by both nuclear and cytoplasmic cap binding proteins. PARN interacts with CUG-BP and KSRP, two RNA binding proteins implicated in mRNA decay and splicing regulation. Antigen: PARN Clone number:--- Immunogen: Recombinant PARN Species reactivity: Human Host species: Rabbit Applications: WB Isotype:--- References:--- Notes: Polyclonal antibody. Recognizes both the 73kDa and 53kDa isoforms. Quantity: 100 µg		100 µg	137.00 EUR

Anticorps anti RNA Polymerase II

Référence	Anticorps	Clone	Qté	Prix Unitaire Euros HT
3518-05	Phosphorylated RNA Polymerase IICatalog #: 3518-05 Phosphorylated RNA Polymerase II (RNA pol II) Antibody RNAPII is an essential component of the RNAP II transcription elongation complex. Recruitment of RNA processing factors to the elongation complex is coordinated by the phosphorylation of Serine-2 and Serine-5 residues within the C-terminal repeat (YSPTSPS) domain of the largest subunit of RNAPII. Antigen: Phosphorylated RNA polymerase II (RNA pol II) Clone number: CDT 8A7 Immunogen: Peptide: 10 repeats of synthetic peptide YSPTSPS using chemically synthesized phospho-ser 5. Species reactivity: Human and S. cerevisiae Host species: Mouse: Balb/c Applications: WB, ELISA Isotype: IgM Reference: Otero G et al. 1999. Mol. Cell. 3:109-118. Notes: Epitope is the C-terminal repeat of the largest subunit of RNAPII Quantity: 100 µg	CTD 8A7	100 µg	266.00 EUR
3518-06	RNA Polymerase IICatalog #: 3518-06 RNA Polymerase II (RNAPII) Antibody RNAPII is an essential component of the RNAP II transcription elongation complex. Recruitment of RNA processing factors to the elongation complex is coordinated by the phosphorylation of Serine-2 and Serine-5 residues within the C-terminal repeat (YSPTSPS) domain of the largest subunit of RNAPII. CTD4H8 can also be used in chromatin immunoprecipitation (ChIP) assays. Antigen: RNA polymerase II (RNA pol II) Clone number: CDT 4H8 Immunogen: Peptide: 10 repeats of synthetic peptide YSPTSPS using chemically synthesized phospho-ser 5. Species reactivity: Human and S. cerevisiae Host species: Mouse: Balb/c Applications: WB, ELISA, IP Isotype: IgG1 Reference: Kristjuhan A et al. 2003. Proc Natl Acad Sci U S A 100:7551-6. Kristjuhan A et al. 2002. Mol Cell 10:925-33. Engelhardt OG et al. 2005. J. Virology 79:5812-5818. Yart A et al. 2005. Mol Cell Biol 25(12): 5052-5060. Li C et al. 2006. Mol Cell Biol 17(9): 3848-3850. Notes: Epitope is the C-terminal repeat of the largest subunit of RNAPII Quantity: 100 µg	CTD 4H8	100 µg	266.00 EUR

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