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Anticorps
	>Protéines d'adhésion cellulaire >Protéines du cycle cellulaire > Cytochrome P450 >Réparation et réplication d'ADN >Protéines de la matrice extracellulaire >Facteurs de croissance >Marqueurs de Leucocyte >Récepteurs >Transduction du Signal >Intermédiaire de signalisation >Protéines structurales >Antigènes spécifiques de tissus >Régulateurs transcriptionnels >Protéines suppresseur de tumeurs >Protéines virales >Beta-galactosidase

Anticorps >

Protéines structurales

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Référence	Anticorps	Clone	Qté	Prix Unitaire Euros HT
3522-03	Clathrin Heavy Chain - Sto 3H9Catalog #: 3522-03 Clathrin Heavy Chain Antibody Clathrin is a component of clathrin-coated pits and vesicles involved in receptor-mediated endocytosis. Antigen: Clathrin heavy chain Clone number: STo 3H9 Immunogen: --- Species Reactivity: --- Host Species: Mouse Applications: WB, IHC (F), IHC (A) Isotype: IgM References: --- Notes: --- Quantity: 100µg	Sto 3H9	100 µg	266.00 EUR
3516-01	Involucrin - SY5Catalog #: 3522-04 Involucrin Monoclonal Antibody Involucrin is a protein precursor of the epidermal cornified envelope and a differentiation marker of human keratinocytes. SY5 is useful for studies of changes in involucrin expression in pathological studies. Antigen: Involucrin Clone number: SY5 Immunogen: Pure involucrin from human keratinocytes Species Reactivity: Human, gorilla, owl, monkey, pig and weakly with dog involucrin Host Species: Female Mouse: Balb/c Applications: WB, IHC (P), IP Isotype: IgG1 References: Hudson D et al. 1992. Hybridoma. 11(3):367-379. Notes: Quantity: 100µg	SY5	100 µg	266.00 EUR
3516-01	Involucrin - SY8Catalog #: 3522-05 Involucrin Monoclonal Antibody Involucrin is a protein precursor of the epidermal cornified envelope and a differentiation marker of human keratinocytes. SY8 is useful for studies of changes in involucrin expression in pathological studies. Antigen: Involucrin Clone number: SY8 Immunogen: Pure involucrin from human keratinocytes Species Reactivity: Human, gorilla, owl, monkey, pig and weakly with dog involucrin Host Species: Female Mouse: Balb/c Applications: WB, IHC (P), IP Isotype: IgG1 References: Hudson D et al. 1992. Hybridoma. 11(3):367-379. Notes: Quantity: 100µg	SY8	100 µg	266.00 EUR

Anticorps anti Kératines

Pour plus de renseignement, cliquez sur les descriptions:

Référence	Anticorps	Clone	Qté	Prix Unitaire Euros HT
3522-06	Keratin 1 - LHK1Catalog #: 3522-06 Keratin 1 Monoclonal Antibody Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratin 1 is differentiation-specific keratin that is one of the predominant keratins in suprabasal keratinocytes in stratified epthelia. Mutations in keratin 1 causes epidermolytic hyperkeratosis. LHK1 is a very good marker for suprabasal keratinocytes. Reactivity on normal human skin sections is suprabasal up to the tratum corneum in interfollicular epidermis. The suprabasal layer in the upper outer root sheath is also reactive. Antigen: Keratin 1 Clone number: LHK1 Immunogen: --- Species Reactivity: Human Host Species: Mouse Applications: WB, IHC (F) (A) (P) Isotype: IgM References: Ishida-Yamamoto A et al. 1991. J. Invest. Dermatol. 97(6):959-968. De Berker D et al. 1995. Exp. Dermatol. 4(6):350-6. Notes: --- Quantity: 100µg	LHK1	100 µg	266.00 EUR
3522-07	Keratin 7, 13, 17, & 18 - LdS 23Catalog #: 3522-07 Keratin 7, 13, 17, & 18 Antibody Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratins 7 and 8 are two closely related type II keratins characteristic of simple epithelia. Keratin 7 is less widespread than keratin 8 and is expressed in sebaceous and sweat glands and some cells of the inner hair root sheath. Keratin 7 is often co-expressed with keratin 19. Keratin 17 is expressed in suprabasal keratinocytes of wounded epidermis. Keratins 8 and 18 are two of the first keratins expressed in the embryo, and persist into adult tissues as the keratin pair representing minimal epithelial keratin expression. Keratins 8 and 18 are major components of all simple epithelia (but not of stratified squamous epithelia) and adenocarcinomas. LdS 23 is useful for studies of epithelial cells and tumour origin. Antigen: Keratin 7,13,17&18 Clone number: LdS 23 Immunogen: Cytoskeletons of the human urothelial RT4 cell line Species Reactivity: Human Host Species: Mouse Applications: IHC (F), IF (F) Isotype: IgG1 References: Notes: --- Quantity: 100µg	LdS 23	100 µg	266.00 EUR
3522-08	Keratin 1 & 10 - LH1Catalog #: 3522-08 Keratin 1 & 10 Antibody Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratin 1 is differentiation-specific keratin that is one of the predominant keratins in suprabasal keratinocytes in stratified epthelia. Mutations in keratin 1 causes epidermolytic hyperkeratosis. Antigen: Keratin 1 & 10 Clone number: LH1 Immunogen: --- Species Reactivity: Human, Murine, Pig Host Species: --- Applications: IHC, WB Isotype: IgG1 References: Brockaert D et al. 1990. Arch. Dermatol. Res. 282:383-391. Markey AC et al. 1991. J. Invest. Dermatol. 97 (5): 763-770. Notes: --- Quantity: 100µg	LH1	100 µg	266.00 EUR
3522-09	Keratin 10 - LH2Catalog #: 3522-09 Keratin 10 Antibody Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratin 10 is differentiation-specific keratin that is one of the predominant keratins in suprabasal keratinocytes in stratified epthelia. Keratin 10 is a suprabasal marker of differentiation in stratified squamous epithelia. Mutations in keratin 10 cause epidermolytic hyperkeratosis. LH2 does not react with any tumour tissue regardless of histological classification. Antigen: Keratin 10 Clone number: LH2 Immunogen: Extract of skin from psoriasis patient Species Reactivity: Human Host Species: Mouse Applications: IHC (F) Isotype: IgG1 References: Brockaert D et al. 1990. Arch. Dermatol. Res. 282:383-391. Porter RM et al. 2000. Lab Invest. 80(11):1701-10. Notes: LH2 is monospecific and has high affinity. Quantity: 100µg	LH2	100 µg	266.00 EUR
3522-10	Keratin 5 & 14 - LH8Catalog #: 3522-10 Keratin 5 & 14 Antibody Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratins 5 and 14 are the predominant keratins in basal layer keratinocytes in stratified epithelia. Keratin 14 is one of two keratins that distinguish stratifying epithelial cell types from simple epithelial cell types. Mutations in keratin 5 or 14 cause the skin blistering disorder epidermolysis bullosa simplex. LH8 may be useful as a basal cell marker and myoepithelial marker in stratified squamous or mixed epithelia. Antigen: Keratin 5 and 14 Clone number: LH8 Immunogen: The 50,000 Mr band (including K14 )cut from an SDS-polyacrylamide gel and Triton X-100 extracted cytoskeleton pellet from cultured human foreskin keratinocytes. Species Reactivity: --- Host Species: Mouse: Balb/c Applications: IHC (F) Isotype: IgM References: de Berker D et al. 1995. Exp. Dermatol. 4(6):350-6 Notes: --- Quantity: 100µg	LH8	100 µg	266.00 EUR
3522-11	Keratin 6 - LHK6Catalog #: 3522-11 Keratin 6 Antibody Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratins 6, 16 and 17 are expressed in suprabasal keratinocytes of wounded epidermis. Keratin 6 is found in acrosyringeal keratinocytes in normal skin. LHK 6 is a very good marker for hyperproliferative keratinocytes. Antigen: Keratin 6 Clone number: LHK6 Immunogen: 11 amino acid sequence GSSTIKYTTTS of K6b C terminal Species Reactivity: Human Host Species: --- Applications: ELISA, WB, IHC (F) (P) (A) Isotype: IgG2ak References: Machesney M et al. 1998. Am. J. Pathol. 152:1133-1141. Porter RM et al. 2000. Lab Invest. 80(11):1701-10. Notes: --- Quantity: 100µg	LHK6	100 µg	266.00 EUR
3522-12	Keratin 6 - LL020 Catalog #: 3522-12 Keratin 6 Antibody Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratins 6 is expressed in suprabasal keratinocytes of wounded epidermis. Keratin 6 is found in acrosyringeal keratinocytes in normal skin. LL020 can be used as a proliferation marker. Antigen: Keratin 6 Clone number: LL020 Immunogen: Carboxy terminal peptide Species Reactivity: --- Host Species: Mouse Applications: WB, IHC (F) (P) Isotype: IgM References: Markey AC et al. 1992. Br. J. Dermatol. 126:154-160 . Hughes. 1996. Br. J. Dermatol. 134:247-256. Notes: --- Quantity: 100µg	LL020	100 µg	266.00 EUR
3522-13	Keratin 18 & 6 (pan-epithial) - LP34 Catalog #: 3522-13 Keratin 18 & 6 (pan-epithelial) Antibody Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratin 6 is expressed in suprabasal keratinocytes of wounded epidermis and in acrosyringeal keratinocytes in normal skin. Keratin 18 is one of the first keratins expressed in the embryo, and persist into adult tissues as the keratin pair representing minimal epithelial keratin expression. Keratin 18 is a major component of all simple epithelia (but not of stratified squamous epithelia) and adenocarcinomas. LP34 stains all human epithelial cells except for the inner hair root sheath and one or two other exceptional cell types. Antigen: Keratin 18 and 6 (pan-epithelial) Clone number: LP34 Immunogen: Human stratum corneum. Species Reactivity: Human Host Species: Mouse Applications: WB, IHC (F) (P) (A) Isotype: IgG1 References: Taylor-Papadimitriou J. et al. 1983. Understanding Breast Cancer. p215. Edited by Rich and Hager. Karashima T & Watt FM. 2002. J. Cell Sci. 115(24):5027-37. Notes: 10 kDa MW. Does not react significantly with keratins 1, 8 and 19. Quantity: 100µg	LP34	100 µg	266.00 EUR
3522-14	Keratin 7 - LP1KCatalog #: 3522-14 Keratin 7 Antibody Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratins 7 and 8 are two closely related type II keratins characteristic of simple epithelia. Keratin 7 is less widespread than keratin 8 and is expressed in sebaceous and sweat glands and some cells of the inner hair root sheath. Keratin 7 is often co-expressed with keratin 19. Antigen: Keratin 7 (some weak reactivity with keratin 8 and other type II keratins) Clone number: LP1K Immunogen: Sonicated cytoskeleton fractions ( insoluble in 1% Nonidet-P40) from SV40 transformed neonatal keratinocytes Species Reactivity: Mammalian, Amphibian Host Species: Mouse: Balb/c Applications: WB, IHC Isotype: IgG1 References: Lane EB et al. 1985. Ann. NY Acad. Sci. 455:241-258. Markey AC et al. 1992. Br. J. Dermatol. 126:154-160. Notes: Immunohistology Poor reactivity with fixed tissue, 54 kDa MW. Some weak reactivity with keratin 8 and other type II keratins Quantity: 100µg	LP1K	100 µg	266.00 EUR
3522-15	Keratin 7 - LP5KCatalog #: 3522-15 Keratin 7 Antibody Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratins 7 and 8 are two closely related type II keratins characteristic of simple epithelia. Keratin 7 is less widespread than keratin 8 and is expressed in sebaceous and sweat glands and some cells of the inner hair root sheath. Keratin 7 is often co-expressed with keratin 19. Antigen: Keratin 7 human; possibly some reaction with keratin 8. Clone number: LP5K Immunogen: Sonicated cytoskeleton fractions ( insoluble in 1% Nonidet-P40) from SV40 transformed neonatal keratinocytes. Species Reactivity: --- Host Species: Mouse: Balb/c Applications: WB, IHC (P) Isotype: IgG1 References: Lane EB et al. 1985. Ann. NY Acad. Sci. 455:241-258. Markey AC et al. 1992. Br. J. Dermatol. 126:154-160. Notes: 54 kDa MW Quantity: 100µg	LP5K	100 µg	266.00 EUR
3522-01	Keratin 8 - LP3K Catalog #: 3522-01 Keratin 8 Monoclonal Antibody Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratins 8 and 18 are two of the first keratins expressed in the embryo, and persist into adult tissues as the keratin pair representing minimal epithelial keratin expression. Keratins 8 and 18 are major components of all simple epithelia (but not of stratified squamous epithelia) and adenocarcinomas. Keratin 8 is the tissue polypeptide antigen (TPA) reported to be present in the serum of cancer patients. Antigen: Keratin 8 Clone number: LP3K Immunogen: Keratin 8 Species Reactivity: Human Host Species: Mouse: Balb/c Applications: WB, IHC Isotype: IgG1 References: Lane EB et al. 1985. Ann. NY Acad. Sci. 455:241-258 Notes: 40 kDa MW Quantity: 100µg	LP3K	100 µg	266.00 EUR
3522-16	Keratin 14 - LL001Catalog #: 3522-16 Keratin 14 Antibody Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Antigen: Keratin 14 Clone number: LL001 Immunogen: --- Species Reactivity: Human, Murine, Pig Host Species: Mouse Applications: WB, IF, IHC (P) (F) Isotype: IgG2a kappa References: Leigh IM et al. 1988. Dermatol. 91:415. D'Alessandro M et al. 2002. J. Cell Sci. 115(22):4341-51. Notes: LL001 characterises stratifing/keratinocyte cell types Quantity: 100µg	LL001	100 µg	266.00 EUR
3522-17	Keratin 15 - LHK 15Catalog #: 3522-17 Keratin 15 Antibody Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratin 15 is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes. Antigen: Keratin 15 (a cytokeratin) Clone number: LHK 15 Immunogen: Peptide sequence of cytokeratin 15 - BSA conjugate Species Reactivity: Human, Mouse, Rat, Bovine Host Species: --- Applications: WB, IF, IHC (P) (F) (A) Isotype: IgG2a References: Waseem A et al. 1999. J. Invest. Dermatol. 112:362-369. Porter RM et al. 2000. Lab Invest. 80(11):1701-10. Notes: --- Quantity: 100µg	LHK 15	100 µg	266.00 EUR
3522-18	Keratin 18 - LC18NCatalog #: 3522-18 Keratin 18 Antibody Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratins 8 and 18 are two of the first keratins expressed in the embryo, and persist into adult tissues as the keratin pair representing minimal epithelial keratin expression. Keratins 8 and 18 are major components of all simple epithelia (but not of stratified squamous epithelia) and adenocarcinomas. Antigen: Keratin 18. Cross reacts with keratin 15. Clone number: LC18N Immunogen: synthetic peptide of N terminus of human keratin 18 (NH2- SFTTRSTFSC) Species Reactivity: --- Host Species: Mouse Applications: WB, IF Isotype: IgG1 References: --- Notes: Does not cross react with mouse. Positive control: HT29 cell line, skin, breast or lung carcinoma Quantity: 100µg	LC18N	100 µg	266.00 EUR
3522-02	Keratin 19 - BA16Catalog #: 3522-02 Keratin 19 Monoclonal Antibody Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratin 19 is the smallest human keratin and is found in many simple and some non-keratinizing stratified squamous epithelia. The degree of keratin 19 positivity in breast cancer distinguishes malignant from benign tumors. Keratin 19 is often co-expressed with keratin 7. Antigen: Keratin 19 Clone number: BA16 Immunogen: Keratin 19 Species Reactivity: Human Host Species: Mouse: Balb/c Applications: WB, IHC (F), IHC (A) Isotype: IgG1 References: Bartek J et al. 1985. J. Cell Sci. 75:17-33. Bartek J et al. 1985. Int. J. Cancer. 36:299-306. Notes: 53 kDa MW Quantity: 100µg	BA16	100 µg	266.00 EUR
3522-19	Keratin 19 - BA17Catalog #: 3522-19 Keratin 19 Monoclonal Antibody Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratin 19 is the smallest human keratin and is found in many simple and some non-keratinising stratified squamous epithelia. The degree of keratin 19 positivity in breast cancer distinguishes malignant from benign tumours. Keratin 19 is often co-expressed with keratin 7. Antigen: Keratin 19 Clone number: BA17 Immunogen: Detergent-insoluble extract of human mammary epithelial organoids Species Reactivity: Human Host Species: Mouse: Balb/c Applications: WB, IHC (F) (A) (P) Isotype: IgG1 References: Bartek J et al. 1985. J. Cell Sci. 75:17-33. Bartek J et al. 1985. Int. J. Cancer. 36:299-306. Notes: --- Quantity: 100µg	BA17	100 µg	266.00 EUR

Référence	Anticorps	Clone	Qté	Prix Unitaire Euros HT
3522-20	TCP-1 - 22bCatalog #: 3522-20 TCP-1 (T Complex Polypeptide-1) Antibody TCP1, (a constituent of chaperone-containing TCP-1, CCT) is a ~60 kDa protein constitutively expressed in almost all eukaryotic cells and upregulated during spermatogenesis. It is found in the cytosol as a subunit of a hetero-oligomeric chaperone that is known to be involved in the folding of actin and tubulin. Antigen: TCP-1 (T-complex polypeptide-1; CCTalpha) Clone number: 22b Immunogen: C-terminal half of the full length murine TCP protein Species Reactivity: Chicken, Rat, Hamster, Mouse, Dog Host Species: Rat Applications: WB, IP Isotype: IgG2a References: Willison K et al. 1989. Cell. 57:621-632. Harrison-Lavoie et al. 1993. EMBO J . 12:2847-2853. Notes: Epitope: 553 LDD-COOH. Does not recognise primate, yeast or xenopus TCP-1 22b is monospecific for TCP-1, not reacting with similar proteins Quantity: 100µg	22b	100 µg	266.00 EUR
3522-21	TCP-1 - 23cCatalog #: 3522-21 TCP-1 (T Complex Polypeptide-1) Antibody TCP1, (a constituent of chaperone-containing TCP-1, CCT) is a ~60 kDa protein constitutively expressed in almost all eukaryotic cells and upregulated during spermatogenesis. It is found in the cytosol as a subunit of a hetero-oligomeric chaperone that is known to be involved in the folding of actin and tubulin. Antigen: TCP-1 (T-complex polypeptide-1; CCTalpha) Clone number: 23C Immunogen: C-terminal half of the full length murine TCP protein Species Reactivity: Mouse, Chicken, Hamster, Rat, Dog Host Species: Rat Applications: WB, IP, IF Isotype: IgG2c References: Willison K et al. 1989. Cell. 57:621-632. Harrison-Lavoie et al. 1993. EMBO J . 12:2847-2853. Sternlicht H et al. 1993. PNAS USA 90:9422-9426. Notes: Epitope: 554 LDD-COOH. 23C binds protein A and is useful for native precipitation of CCT and golgi coatomer. Does not recognise primate, xenopus or yeast TCP-1 Quantity: 100µg	23c	100 µg	266.00 EUR
3522-22	TCP-1 - 84aCatalog #: 3522-22 TCP-1 (T Complex Polypeptide-1) Antibody TCP1, (a constituent of chaperone-containing TCP-1, CCT) is a ~60 kDa protein constitutively expressed in almost all eukaryotic cells and upregulated during spermatogenesis. It is found in the cytosol as a subunit of a hetero-oligomeric chaperone that is known to be involved in the folding of actin and tubulin. Antigen: TCP-1 (T-complex polypeptide-1; CCTalpha) Clone number: 84a Immunogen: C-terminal half of the full length murine TCP protein Species Reactivity: Mouse, Chicken, Hamster, Monkey, Human Host Species: Rat Applications: WB, IP Isotype: IgG2a References: Willison K et al. 1989. Cell. 57:621-632. Harrison-Lavoie et al. 1993. EMBO J . 12:2847-2853. Notes: Epitope: 542 HGSYE (in the C terminus). 84a can be used together with 91a for immunoprecipitation of CCT. 84a recognises a protein of 80kDa in LK-35.2 cells Quantity: 100µg	84a	100 µg	266.00 EUR
3522-23	TCP-1 alpha - 91a	91a	100 µg	266.00 EUR
3522-24	Vimentin - J144	J144	100 µg	266.00 EUR

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