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PROTEOMIC SOLUTIONS

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GAPDH ELISA Test Kit


Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is an enzyme that catalyzes the sixth step of glycolysis where it serves to break down glucose for energy and carbon molecules.  GAPDH has also been found to play a role in membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, prostate cancer progression, programmed neuronal cell death, DNA replication, and DNA repair. 


Particularly useful when studying RNAi induced gene silencing, the MaxSuppressor™ GAPDH ELISA kit can be used to detect GAPDH knockdown in tissues from animals that have been treated with a GAPDH RNAi agent.  With this quantitative assay, users can rapidly analyze the impact of siRNA or shRNA on GAPDH levels in mouse, human or rat organs and body fluids including serum.


Kit Features:

  1. Allows users to quantify the level of GAPDH in tissues for lysate normalization.
  2. Allows users to monitor serum GAPDH levels which is an indicator of myocardial infarction and liver cirrhosis (A,B).
  3. Allows for quantitative analysis of GAPDH in cells and tissues.
  4. Includes lysis buffer for the extraction of total proteins from mammalian tissues and cell lines.

References: 

    A. Elevated Serum Glyceraldehyde Phosphate Dehydrogenase Activity     Following Acute Myocardial Infarction.  Joel S. Karliner M.D.1; Martin     P. Gander M.D.2; and Burton E. Sobel M.D. Chest. 1971; 60:318-     323.

    B. High serum glyceraldehyde-3-phosphate dehydrogenase levels in     patients with liver cirrhosis. Shibuya A, Ikewaki N. Hepatol Res.     2002     Mar;22(3):174-179.

     

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Reference
Description
Qté
Prix unitaire Euros HT

3401

 MaxSuppressor™ GAPDH ELISA kit
1 kit
493.00 EUR

 

 

 

 

 

 

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